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. 2022 Jul 7;2022:3862122. doi: 10.1155/2022/3862122

Figure 6.

Figure 6

NOX4/NLRP3 signaling pathway affected the effects of the HUCMSC in vitro model of premature ovarian failure by miR-100-5p heat map and combine sample correlation (a), volcanic map (b), result analysis (c), NOX4 mRNA (d, e), luciferase reporter levels and KLF13 constructed targeting miR-100-5p (f), and NOX4 protein expression (g, h). Control: control group; low/med/high: low/med/high of the HUCMSC group. Vector: negative control group; miR-100-5p: overexpression of miR-100-5p group; sh-nc: sh-negative control group; sh-miR-100-5p: downregulation of miR-100-5p group; HUCMSCs: HUCMSC group; ∗∗p < 0.01 compared with vector or sh-negative control group.