Figure 8.

Transfection of the miR-128-5p mimic and inhibitor affected SM22ɑ, p21 and p27 expression, and VSMC proliferation. (a) Western blotting was performed to determine the expression of sm22ɑ, p21, and p27. These data are representative of 3 experiments. The results are described as the mean ± SD (n = 3). ^∗P < 0.05 versus mimic NC and ^#P < 0.05 versus inhibitor NC. (b) Immunocytochemistry staining of incorporated BrdU in VSMCs was performed to investigate the proliferation of VSMCs. These data are representative of 3 experiments. The results are described as the mean ± SD (n = 3). ^∗P < 0.05 versus mimic NC, ^#P < 0.05 versus inhibitor NC, and ΔP < 0.05 versus mimic NC.