Table 1.
Clinical characteristics of male and female patients with colon cancer.
| MCC without metastasis | MCC with metastasis | FCC without metastasis | FCC with metastasis | P value^ | P value∗ | P value# | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| N = 47277 | % 82.1 | N = 10320 | % 17.9 | N = 47625 | % 84.4 | N = 8817 | %15.6 | ||||
| Age at diagnosis (year) | .000∗∗ | .000∗∗ | .000∗∗ | ||||||||
| ≤60 | 17668 | 37.4 | 4430 | 42.9 | 14952 | 31.4 | 3546 | 40.2 | |||
| >60 | 29609 | 62.6 | 5890 | 57.1 | 32673 | 68.6 | 5271 | 59.8 | |||
| Race | .000∗∗ | .000∗∗ | .000∗∗ | ||||||||
| Black | 5541 | 11.7 | 1652 | 16.0 | 6292 | 13.2 | 1617 | 18.3 | |||
| White | 36598 | 77.4 | 7727 | 74.9 | 36343 | 76.3 | 6362 | 72.2 | |||
| Others | 4570 | 9.67 | 919 | 8.91 | 4522 | 9.50 | 822 | 9.32 | |||
| Unknown | 568 | 1.20 | 22 | 0.21 | 468 | 0.98 | 16 | 0.18 | |||
| Primary site | .000∗∗ | .000∗∗ | .000∗∗ | ||||||||
| Right colon | 22445 | 47.5 | 4243 | 41.1 | 26482 | 55.6 | 4183 | 47.4 | |||
| Left colon | 23686 | 50.1 | 5264 | 51.0 | 20023 | 42.0 | 3812 | 43.2 | |||
| Overlapping lesion | 532 | 1.13 | 138 | 1.34 | 570 | 1.20 | 132 | 1.50 | |||
| Unknown | 614 | 1.30 | 675 | 6.54 | 550 | 1.15 | 690 | 7.83 | |||
| Histopathology type | .000∗∗ | 0.912 | .000∗∗ | ||||||||
| Adenocarcinoma | 45618 | 96.5 | 9742 | 94.4 | 45729 | 96.0 | 8319 | 94.4 | |||
| Others | 1659 | 3.51 | 578 | 5.60 | 1896 | 3.98 | 498 | 5.65 | |||
| Pathology grade | .000∗∗ | 0.063 | .000∗∗ | ||||||||
| (I) Well-differentiated | 4399 | 9.30 | 382 | 3.70 | 4197 | 8.81 | 333 | 3.78 | |||
| (II) Moderately | 30045 | 63.6 | 5326 | 51.6 | 29583 | 62.1 | 4390 | 49.8 | |||
| (III) Poorly differentiated | 5895 | 12.5 | 1841 | 17.8 | 7334 | 15.4 | 1577 | 17.9 | |||
| (IV) Undifferentiated | 1244 | 2.63 | 348 | 3.37 | 1615 | 3.39 | 337 | 3.82 | |||
| Unknown | 5694 | 12.0 | 2423 | 23.5 | 4896 | 10.3 | 2180 | 24.7 | |||
| T | 0.000 | 0.697 | 0.000 | ||||||||
| T0-T2 | 18260 | 38.6 | 1276 | 33.9 | 17413 | 36.6 | 1055 | 12.0 | |||
| T3-T4 | 27645 | 58.5 | 6175 | 59.8 | 28741 | 60.3 | 5293 | 60.0 | |||
| Unknown | 1372 | 2.9 | 2869 | 27.8 | 1471 | 3.1 | 2469 | 28.0 | |||
| N | 0.000 | 0.117 | 0.000 | ||||||||
| N0 | 30765 | 65.1 | 3199 | 31.0 | 30468 | 64.0 | 2786 | 31.6 | |||
| N1 | 10342 | 21.9 | 3382 | 32.8 | 10681 | 22.4 | 2746 | 31.1 | |||
| N2 | 5501 | 11.6 | 2520 | 24.4 | 5788 | 12.2 | 2222 | 25.2 | |||
| Unknown | 699 | 1.4 | 1219 | 11.8 | 688 | 1.4 | 1063 | 12.1 | |||
| Surgery | .000∗∗ | 0.356 | .000∗∗ | ||||||||
| No | 2635 | 5.57 | 4653 | 45.1 | 2625 | 5.51 | 3958 | 44.9 | |||
| Yes | 44578 | 94.3 | 5647 | 54.7 | 44939 | 94.4 | 4849 | 55.0 | |||
| Unknown | 64 | 0.14 | 20 | 0.19 | 61 | 0.13 | 10 | 0.11 | |||
| Radiotherapy | .000∗∗ | 0.145 | .000∗∗ | ||||||||
| No | 45314 | 95.8 | 9715 | 94.1 | 46271 | 97.2 | 8344 | 94.6 | |||
| Yes | 1963 | 4.15 | 605 | 5.86 | 1354 | 2.84 | 473 | 5.36 | |||
| Chemotherapy | .000∗∗ | .000∗∗ | .000∗∗ | ||||||||
| No | 33412 | 70.7 | 3473 | 33.7 | 34496 | 72.4 | 3227 | 36.6 | |||
| Yes | 13865 | 29.3 | 6847 | 66.3 | 13129 | 27.6 | 5590 | 63.4 | |||
| Marital status | .000∗∗ | .000∗∗ | .000∗∗ | ||||||||
| Married | 28733 | 60.8 | 5875 | 56.9 | 20114 | 42.2 | 3757 | 42.6 | |||
| Unmarried | 15497 | 32.8 | 3931 | 38.1 | 24252 | 50.9 | 4600 | 52.2 | |||
| Unknown | 3047 | 6.44 | 514 | 4.98 | 3259 | 6.84 | 460 | 5.22 | |||
| Insurance situation | .000∗∗ | 0.011∗ | .000∗∗ | ||||||||
| Insurance | 44271 | 93.6 | 9549 | 92.5 | 45093 | 94.7 | 8254 | 93.6 | |||
| No insurance | 1658 | 3.51 | 585 | 5.67 | 1286 | 2.70 | 419 | 4.75 | |||
| Unknown | 1348 | 2.85 | 186 | 1.80 | 1246 | 2.62 | 144 | 1.63 | |||
FCC: female colon cancer; MCC: male colon cancer. ^Comparison between male colon cancer without metastasis and male colon cancer with metastasis. ∗Comparison between male colon cancer with metastasis and female colon cancer with metastasis. #Comparison between female colon cancer without metastasis and female colon cancer with metastasis. ∗P < .05; ∗∗P < .001.