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. 2022 Jul 7;2022:5498743. doi: 10.1155/2022/5498743

Figure 3.

Figure 3

SIRT4 overexpression suppresses xenograft tumor growth in vivo. (a) Overexpression of SIRT4 dramatically inhibits subcutaneous tumor growth in nude mice. (b) The volumes of xenograft tumors were measured by the vernier caliper every 6 days. (c) The weight of tumors in the PC-3-Vector and PC-3-SIRT4 groups. (d) The results of HE staining and IHC indicate that overexpression of SIRT4 reduced the expression of Ki-67. Magnification ×100, scale bar = 100 μm, magnification ×400, scale bar = 25 μm, ∗P < 0.05∗∗P < 0.01, ∗∗∗P < 0.001.