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Table 3 . Evaluation of participants by in-hospital mortality and ICU admission (continued) .

Variable

D-dimer

Lactate

NEWS2

NEWS2 + lactate

NEWS2 + D-dimer

NEWS2 + lactate + D-dimer

ICU admission

AUC (95% CI)

0.745 (0.658–0.832)

0.589 (0.469–0.710)

0.760 (0.675–0.845)

0.774 (0.690–0.859)

0.776 (0.692–0.860)

0.778 (0.694–0.862)

p value

< 0.001

0.124

< 0.001

< 0.001

< 0.001

< 0.001

Cut-off level

0.16

1.65

2.50

4.55

3.16

6.40

Sensitivity (%)

85.7

57.1

85.7

82.1

85.7

67.9

Specificity (%)

63.0

58.8

56.9

64.4

63.4

79.6

PPV (%)

23.1

15.2

20.5

23.0

23.3

30.2

NPV (%)

97.1

91.4

96.9

96.5

97.2

95.0

Mortality

AUC (95% CI)

0.768 (0.671–0.865)

0.695 (0.563–0.827)

0.735 (0.634–0.836)

0.757 (0.647–0.867)

0.752 (0.656–0.848)

0.764 (0.655–0.873)

p value

0.001

0.067

0.003

0.001

0.002

0.001

Cut-off level

0.17

1.65

2.5

4.15

3.16

4.54

Sensitivity (%)

92.9

71.4

85.7

85.7

85.7

85.7

Specificity (%)

61.7

58.7

54.3

55.7

60.4

57.8

PPV (%)

12.9

9.5

10.3

10.5

11.7

11.0

NPV (%)

99.3

97.1

98.4

98.5

98.6

98.5