Fig. 5.
Weight-adjusted changes in cardiometabolic health markers from baseline in women and men (n=2223). Values are estimated marginal mean (95% CI) changes from baseline in FPG (a), 2 h plasma glucose (b), HbA1c (c), triacylglycerol (d), HDL-cholesterol (e), LDL-cholesterol (f), SBP (g) and DBP (h). Analyses were performed using a linear mixed model including sex, age, ethnicity, baseline BMI, baseline smoking status, baseline alcohol consumption, baseline values of the outcome being considered, time-varying percentage weight loss from baseline, baseline energy intake and PA, time-varying changes in energy intake and PA from baseline, intervention arm, time and interaction of time and sex as fixed covariates and participant identifier and intervention centre as random effects. Post hoc pairwise comparisons (independent samples t tests) were performed to compare women and men at each time point, where appropriate. Women vs men *p<0.05, **p<0.01 and ***p<0.001