Table 3.
Comparisons of total outcomes between groups.
| Group | Successful extubation | Failed weaning | p value | ||
|---|---|---|---|---|---|
| Number | Number | ||||
| Post-weaning period | |||||
| Weight (kg) | 140 | 59.9 ± 14.5 | 140 | 60.2 ± 11.6 | 0.665 |
| BMI (kg/m2) | 140 | 22.7 ± 4.84 | 140 | 23.0 ± 3.83 | 0.395 |
| APACHE II score | 79 | 10.1 ± 6.75 | 64 | 20.6 ± 7.80 | < 0.001** |
| Energy delivery (kcal/kg/day) | 140 | 27.8 ± 9.1 | 140 | 25.6 ± 7.5 | 0.199 |
| Protein intake (g/kg/day) | 140 | 1.14 ± 0.42 | 140 | 1.03 ± 0.36 | 0.140 |
| Clinical benefits | |||||
| RCC LOS (day) | 140 | 19.9 ± 10.0 | 28.5 ± 14.5 | < 0.001** | |
| Length of stay (day) | 140 | 48.3 ± 19.5 | 56.3 ± 26.9 | 0.001** | |
| NHI premium cost (USD) | 138 | $18,555 (13,498–27,175) | $26,312 (17,599–32,824) | < 0.001** | |
| Mortality (%) | 17 | 12.1% | 36 | 25.7% | 0.016* |
| Post-weaning lab data | |||||
| Albumin (g/dl) | 108 | 3.29 ± 0.6 | 100 | 3.09 ± 0.6 | 0.026* |
| Prealbumin (mg/dl) | 44 | 21.6 ± 6.9 | 38 | 22.0 ± 8.1 | 0.970 |
| Hemoglobin (g/dl) | 125 | 11.0 ± 2.2 | 121 | 9.6 ± 2.0 | < 0.001** |
| BUN (mg/dl) | 129 | 35.9 ± 35.4 | 124 | 42.8 ± 35.4 | 0.027* |
| Creatinine (mg/dl) | 134 | 1.69 ± 2.4 | 130 | 1.73 ± 1.6 | 0.102 |
| Potassium (mmol/l) | 137 | 4.19 ± 067 | 132 | 4.21 ± 0.83 | 0.569 |
| Calcium (mg/dl) | 37 | 8.31 ± 1.08 | 26 | 8.56 ± 0.91 | 0.255 |
| Magnesium (mg/dl) | 21 | 2.3 (1.9–2.4) | 18 | 2.3 (2.0–2.6) | 0.460 |
| Phosphorus (mg/dl) | 30 | 3.8 (3.1–6.0) | 19 | 3.7 (3.2–5.2) | 0.954 |
| CRP (mg/dl) | 136 | 1.57 (0.59–4.21) | 125 | 4.41 (1.53–8.45) | < 0.001** |
Continuous data are expressed as mean ± SD and p values are from independent t test. Categorical data are expressed as n (%) and the p values are from the Pearson chi-square test. NHI premium cost and laboratory values are presented as median (25th to 75th percentiles), with p values from the Mann–Whitney U test. Mortality rates were compared using log-rank tests for survival analysis. *p value < 0.05 and **p value < 0.01 are considered statistically significant and extremely significant, respectively.
BMI Body Mass Index, APACHE II score Acute physiology assessment and chronic health evaluation II score, RCC LOS Respiratory care center length of stay, NHI National Health Insurance, BUN blood urea nitrogen, CRP high sensitivity C reactive protein.