Table 5.

Risk factors for major complications based on univariate and multivariate logistical regression analyses

Characteristics	Univariate logistical analysis			Multivariate logistical analysis
	OR	95% CI	p value	OR	95% CI	p value
Age
< 65 years	Reference
≥ 65 years	1.216	0.688–2.149	0.500
Gender
Female	Reference			Reference
Male	1.452	0.767–2.748	0.252	0.989	0.423–2.314	0.980
BMI
< 25 kg/m2	Reference			Reference
≥ 25 kg/m2	2.872	1.478–5.580	0.002	2.936	1.088–7.928	0.034
Preoperative serum albumin level
≥ 40 g/L	Reference
< 40 g/L	0.867	0.469–1.602	0.648
ASA score			0.681
I	Reference
II	1.332	0.495–3.584	0.570
III	0.640	0.067–6.142	0.699
Neoadjuvant chemotherapy
No	Reference
Yes	0.891	0.373–2.358	0.891
T stage
T1–2	Reference
T3–4	1.003	0.562–1.790	0.992
N stage
N0	Reference
N1–3	1.259	0.706–2.244	0.435
Type of resection			0.002			0.148
Distal gastrectomy	Reference			Reference
Proximal gastrectomy	5.755	2.126–15.575	0.001	4.933	0.931–26.124	0.061
Total gastrectomy	1.887	0.990–3.596	0.054	1.309	0.430–3.982	0.636
Combined resection
No	Reference
Yes	0.714	0.086–5.920	0.755
Operation time
≤ 300 min	Reference			Reference
> 300 min	3.009	1.614–5.608	0.001	2.108	0.706–6.293	0.181
Blood loss
< 100 ml	Reference			Reference
≥ 100 ml	1.751	0.988–3.105	0.055	0.958	0.374–2.452	0.928
POD3/2 CRP
≤ 1.0	Reference
> 1.0	37.422	15.971–87.687	< 0.001	42.548	16.967–106.700	< 0.001

OR odds ratio; CI confidence interval; BMI body mass index; ASA American Society of Anesthesiologists; POD3/2 CRP the ratio of CRP level on postoperative day 3 to day 2