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. 2022 Feb 23;15:1237–1248. doi: 10.2147/JIR.S351660

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© 2022 Dai et al.

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P2X7R promote Th17 cells and pro-inflammatory cytokines production. (A) The expressions of CD4⁺IL-17⁺Th17 cells among the three groups at 12h. (B) The levels of CD4⁺IL-17⁺Th17 cells in ATP group, BBG group and Control group at each time point. (C-E) The serum levels of IL-1β, IL-6 and IL-17 of the three groups at each time point. (F) The expression of IL-17 mRNA among three groups at each time point. * P<0.05, ** P< 0.01, *** P< 0.001.