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MIC and HC50 activities of peptides against bacterial strains and murine red blood cells (RBCs).
| Peptides | MIC in μg/mL | GM of MIC | HC50 in μg/mL | Therapeutic index (HC50/GM of MIC) | Fold | ||
|---|---|---|---|---|---|---|---|
| Escherichia coli O175:H7 | Salmonella typhimurium NCTC 74 | Staphylococcus aureus ATCC 9155 | |||||
| N-15 Cath-2 | 64 | 8 | ≥ 128 | 19.95 | 97.76 | 2.4 | 10 |
| DP1 (LLK) | 16 | 32 | 16 | 10.2 | 216 | 10.7 | 4.46 |
| DP2 (LLR) | 8 | 32 | 32 | 10.08 | 145 | 6.7 | 2.8 |
| DP3 (L3) | 32 | 16 | 32 | 25.4 | 24.62 | 0.5 | 0.2 |
