Table 7.

Incremental costs associated with treatment complications^a

	Cost difference
	Least	Greatest
Total [58, 59, 61]	− $4688 [61]	$21,723 [58]
Inpatient [58, 59, 61]	$3982 [58]	− $26,720 [61]
Outpatient [58, 59, 61]	$1212 [61]	− $1716 [58]
Medication [58, 59]	$10,463 [59]	$19,833 [61]
ED [58, 61]	− $158 [61]	− $1289 [59]

Costs reflect the differences with treatment as the baseline (with minus without). All costs were adjusted to 2019 US$ using the Consumer Price Index. For additional details and study-specific adjustments, see Appendix Table B4

ED emergency department, MPR medication possession ratio

^aTreatment category includes studies that reported results stratified by adherence and included the adherent category, defined as MPR ≥ 80%

No treatment category includes studies that reported results stratified by adherence and included the non-adherent category, defined as MPR < 80%