Table 2.
Association of clinicopathological characteristics with overall survival using univariate or multivariate Cox regression analysis.
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | p-value | Hazard ratio (95% CI) | p-value | ||
| Age (≤60 vs. >60) | 501 | 1.252 (0.956–1.639) | 0.102 | ||
| Gender (Female vs. Male) | 501 | 0.764 (0.574–1.018) | 0.066 | 0.975 (0.611–1.556) | 0.915 |
| Clinical stage (Stage I and Stage II vs. Stage III and Stage IV) | 487 | 1.217 (0.878–1.688) | 0.238 | ||
| T stage (T1 and T2 vs. T3 and T4) | 486 | 1.245 (0.932–1.661) | 0.137 | ||
| N stage (N0 vs. N1 and N2 and N3) | 479 | 1.263 (0.964–1.653) | 0.090 | 1.603 (0.994–2.585) | 0.053 |
| M stage (M0 vs. M1) | 476 | 4.745 (1.748–12.883) | 0.002 | 2.041 (0.241–17.265) | 0.513 |
| Primary therapy outcome (PD and SD and PR vs. CR) | 417 | 0.182 (0.124–0.268) | <0.001 | 0.209 (0.125–0.350) | <0.001 |
| Histologic grade (G1 vs. G2 and G3) | 480 | 1.592 (1.025–2.474) | 0.039 | 1.275 (0.590–2.756) | 0.537 |
| Lymphovascular invasion (No vs. Yes) | 340 | 1.699 (1.211–2.384) | 0.002 | 1.657 (1.025–2.680) | 0.039 |
| Lymph node neck dissection (No vs. Yes) | 498 | 0.731 (0.526–1.016) | 0.062 | 0.667 (0.289–1.543) | 0.344 |
| DCBLD1(High vs. Low) | 501 | 0.707 (0.540–0.925) | 0.012 | 0.631 (0.410–0.971) | 0.036 |
| Radiation therapy (No vs. Yes) | 440 | 0.613 (0.452–0.831) | 0.002 | 0.534 (0.327–0.871) | 0.012 |
| Race (White vs. Black or African American and Asian) | 485 | 1.470 (0.973–2.220) | 0.067 | 1.256 (0.654–2.409) | 0.494 |
Bold values P<0.05