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. 2022 Jul 1;9:899290. doi: 10.3389/fcvm.2022.899290

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Copyright © 2022 Rodrigues, Vicenzi, Bellocchi, Beretta, Carandina, Tobaldini, Carugo and Montano.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlations between systolic pulmonary artery pressure and cardiac autonomic modulation in SSc patients. PAPs, systolic pulmonary artery pressure; Δ0V%, [(0V% in supine position-0V% in orthostatic position)/0V% in supine position]. 0V% and 2LV% are non-linear heart rate variability markers of sympathetic and vagal modulation. Plots (A,B) represent cardiac sympathetic modulation at rest and sympathetic dynamic response to ORT, respectively. Plots (C,D) represent cardiac vagal modulation at rest and vagal dynamic response to ORT, respectively. *p < 0.05 from Spearman’s correlation.