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. 2022 Jul 1;13:928752. doi: 10.3389/fendo.2022.928752

Table 1.

Characteristics of the study population based on BLL quartiles.

Blood lead (μg/dL)
total Q1 (0.18-0.59) Q2 (0.59-0.82) Q3 (0.82-1.20) Q4 (>1.20) P value
Number of subjects (n) 5583 1386 1386 1391 1420
Age (years) 13.49 ± 3.35 14.09 ± 3.06 13.65 ± 3.36 13.28 ± 3.45 12.70 ± 3.43 <0.001
Gender (%) <0.001
Men 53.27% 36.74% 53.72% 60.84% 66.86%
Women 46.73% 63.26% 46.28% 39.16% 33.14%
Race/ethnicity (%) <0.001
Mexican American 13.77% 14.41% 11.98% 12.77% 16.39%
Other Hispanic 5.85% 5.11% 5.36% 6.20% 7.11%
Non-Hispanic White 59.28% 67.64% 62.35% 56.40% 47.00%
Non-Hispanic Black 13.94% 8.39% 12.89% 15.81% 20.87%
Other Race (Including Multi-Racial) 7.16% 4.45% 7.42% 8.83% 8.63%
PIR 2.61 ± 1.60 3.00 ± 1.60 2.82 ± 1.55 2.41 ± 1.58 2.01 ± 1.49 <0.001
Blood urea nitrogen (mmol/L) 3.67 ± 0.96 3.62 ± 0.90 3.64 ± 0.93 3.73 ± 1.09 3.71 ± 0.93 0.007
Serum total calcium (mmol/L) 2.41 ± 0.06 2.41 ± 0.07 2.41 ± 0.06 2.42 ± 0.07 2.42 ± 0.06 <0.001
Serum phosphorus (mmol/L) 1.42 ± 0.18 1.40 ± 0.17 1.42 ± 0.18 1.44 ± 0.19 1.44 ± 0.18 <0.001
Cholesterol (mmol/L) 4.24 ± 0.64 4.21 ± 0.69 4.24 ± 0.64 4.24 ± 0.61 4.27 ± 0.60 0.188
Total protein (g/L) 7.20 ± 0.33 7.19 ± 0.34 7.20 ± 0.35 7.19 ± 0.33 7.21 ± 0.30 0.508
Serum uric acid (mmol/L) 301.80 ± 58.97 291.10 ± 60.81 303.55 ± 59.76 304.96 ± 55.87 310.74 ± 56.69 <0.001
BMI (kg/m2) 22.49 ± 5.68 23.61 ± 5.91 22.95 ± 5.81 22.15 ± 5.53 21.27 ± 5.19 <0.001
Total femur BMD (g/cm2) 0.90 ± 0.19 0.92 ± 0.18 0.92 ± 0.19 0.89 ± 0.19 0.87 ± 0.19 <0.001
Femur neck
(g/cm2)
0.84 ± 0.17 0.86 ± 0.16 0.85 ± 0.18 0.82 ± 0.17 0.81 ± 0.17 <0.001
Total spine BMD (g/cm2) 0.85 ± 0.20 0.90 ± 0.19 0.86 ± 0.20 0.83 ± 0.20 0.79 ± 0.20 <0.001
Blood lead (μg/dL) 1.04 ± 0.87

Mean ± SD for continuous variables: the P value was calculated by the weighted linear regression model. (%) for categorical variables. The P value was calculated by the weighted chi-square test. BLL Blood lead levels. BMD bone mineral density. PIR poverty income ratio. BMI body mass index.