Table 2.

Linear regression analyses: relationship between ePVS and MoCA scores or WMH Volume.

Effect	β	R 2	P -Value	SE	95% CI
Model 1: dependent variable—MoCA (N =105)
Total ePVS	−0.352	0.113	<0.001**	0.099	−0.549	−0.156
CS ePVS	−0.351	0.118	<0.001**	0.097	−0.543	−0.160
BG ePVS	−0.186	0.033	0.070	0.102	−0.388	0.016
HPC ePVS	−0.056	0.003	0.561	0.096	−0.246	0.134
MB ePVS	−0.073	0.006	0.447	0.096	−0.264	0.117
Model 2: dependent variable—WMH volume (N = 104)
Total ePVS	0.245	0.069	0.010*	0.093	0.060	0.430
CS ePVS	0.206	0.053	0.027*	0.092	0.023	0.388
BG ePVS	0.324	0.118	<0.001**	0.089	0.148	0.500
HPC ePVS	0.016	<0.001	0.860	0.088	−0.159	0.190
MB ePVS	−0.138	0.025	0.117	0.087	−0.312	0.035

MoCA, Montreal Cognitive Assessment; ePVS, enlarged perivascular space; CS, centrum semiovale; BG, basal ganglia; HPC, hippocampus; MB, midbrain; WMH, white matter hyperintensity.

Both Model 1 and Model 2 adjusted for age, gender, years of education, and eTIV.

^*P ≤ 0.05.

^**P ≤ 0.01.