Table 2.
No. of patients(N = 235,872) | No. of Events(N = 2,971) | Incidence rate per 10,000 person years (95% CI) | 10-Year cumulative rate | P-value by log rank test | Crude HR(95% CI) | P-value | |
---|---|---|---|---|---|---|---|
Age at first delivery | <.0001 | ||||||
<30 | 115507 | 849 | 5.92 (5.53-6.33) | 0.39 (0.35-0.42) | Ref | ||
30-39 | 116381 | 2021 | 14.00 (13.40-14.62) | 1.01 (0.95-1.07) | 2.36 (2.18, 2.56) | <.0001 | |
40-49 | 3984 | 101 | 20.56 (16.92-24.99) | 2.09 (1.65-2.54) | 3.47 (2.82, 4.26) | <.0001 | |
Age at last delivery | <.0001 | ||||||
20-29 | 66222 | 439 | 5.34 (4.86-5.86) | 0.38 (0.34-0.43) | Ref | ||
30-39 | 163948 | 2396 | 11.77 (11.31-12.25) | 0.82 (0.78-0.87) | 2.20 (1.99, 2.44) | <.0001 | |
40-49 | 5702 | 136 | 19.32 (16.33-22.86) | 1.85 (1.50-2.20) | 3.62 (2.99, 4.39) | <.0001 | |
Number of delivery | <.0001 | ||||||
1 | 105091 | 1681 | 12.92 (12.32-13.56) | 1.00 (0.94-1.06) | Ref | ||
2 | 118202 | 1194 | 8.12 (7.67-8.60) | 0.52 (0.48-0.56) | 0.63 (0.58, 0.68) | <.0001 | |
>=3 | 12579 | 96 | 6.12 (5.01-7.47) | 0.39 (0.28-0.50) | 0.47 (0.38, 0.58) | <.0001 | |
Interval of delivery (women with two deliveries) | 0.0973 | ||||||
≥ 10 months, < 12 months | 570 | 9 | 12.70 (6.61-24.42) | 0.70 (0.02-1.39) | 2.48 (1.18, 5.22) | 0.0170 | |
≥ 12 months, < 24 months | 29231 | 295 | 8.12 (7.25-9.11) | 0.58 (0.49-0.67) | 1.59 (1.09, 2.31) | 0.0159 | |
≥ 24 months, < 36 months | 41757 | 421 | 8.12 (7.38-8.93) | 0.50 (0.44-0.57) | 1.59 (1.10, 2.30) | 0.0144 | |
≥ 36 months, < 48months | 26936 | 273 | 8.15 (7.23-9.17) | 0.50 (0.42-0.59) | 1.59 (1.09, 2.32) | 0.0159 | |
≥ 48 months, < 60 months | 15187 | 166 | 8.78 (7.54-10.22) | 0.51 (0.40-0.63) | 1.71 (1.16, 2.53) | 0.0066 | |
≥ 60 months | 4521 | 30 | 5.25 (3.67-7.51) | 0.38 (0.20-0.55) | Ref |