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. 2022 Jul 1;12:889433. doi: 10.3389/fonc.2022.889433

Table 2.

Incidence rate of breast cancer in women who had first delivery in 2007.

No. of patients(N = 235,872) No. of Events(N = 2,971) Incidence rate per 10,000 person years (95% CI) 10-Year cumulative rate P-value by log rank test Crude HR(95% CI) P-value
Age at first delivery <.0001
 <30 115507 849 5.92 (5.53-6.33) 0.39 (0.35-0.42) Ref
 30-39 116381 2021 14.00 (13.40-14.62) 1.01 (0.95-1.07) 2.36 (2.18, 2.56) <.0001
 40-49 3984 101 20.56 (16.92-24.99) 2.09 (1.65-2.54) 3.47 (2.82, 4.26) <.0001
Age at last delivery <.0001
 20-29 66222 439 5.34 (4.86-5.86) 0.38 (0.34-0.43) Ref
 30-39 163948 2396 11.77 (11.31-12.25) 0.82 (0.78-0.87) 2.20 (1.99, 2.44) <.0001
 40-49 5702 136 19.32 (16.33-22.86) 1.85 (1.50-2.20) 3.62 (2.99, 4.39) <.0001
Number of delivery <.0001
 1 105091 1681 12.92 (12.32-13.56) 1.00 (0.94-1.06) Ref
 2 118202 1194 8.12 (7.67-8.60) 0.52 (0.48-0.56) 0.63 (0.58, 0.68) <.0001
 >=3 12579 96 6.12 (5.01-7.47) 0.39 (0.28-0.50) 0.47 (0.38, 0.58) <.0001
Interval of delivery (women with two deliveries) 0.0973
≥ 10 months, < 12 months 570 9 12.70 (6.61-24.42) 0.70 (0.02-1.39) 2.48 (1.18, 5.22) 0.0170
≥ 12 months, < 24 months 29231 295 8.12 (7.25-9.11) 0.58 (0.49-0.67) 1.59 (1.09, 2.31) 0.0159
≥ 24 months, < 36 months 41757 421 8.12 (7.38-8.93) 0.50 (0.44-0.57) 1.59 (1.10, 2.30) 0.0144
≥ 36 months, < 48months 26936 273 8.15 (7.23-9.17) 0.50 (0.42-0.59) 1.59 (1.09, 2.32) 0.0159
≥ 48 months, < 60 months 15187 166 8.78 (7.54-10.22) 0.51 (0.40-0.63) 1.71 (1.16, 2.53) 0.0066
≥ 60 months 4521 30 5.25 (3.67-7.51) 0.38 (0.20-0.55) Ref