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. 2022 Jul 1;12:889433. doi: 10.3389/fonc.2022.889433

Table 4.

Univariate analysis of survival (overall survival) for breast cancer patients.

No of patient (n = 2971) No of event (n = 145) Incidence rate per 10,000 person-years (95% CI) 5-Year overall survival 10-Year overall survival p-value* Unadjusted HR (95% CI) p-value**
Age at diagnosis of breast cancer 0.0391
 20-29 35 5 146.69 (61.06-352.44) 91.43 (82.15-100.00) 84.21 (71.34-97.08) ref
 30-39 1123 87 129.06 (104.60-159.23) 92.64 (90.96-94.33) 88.80 (86.28-91.31) 0.73 (0.30, 1.81) 0.4988
 40-49 1740 52 89.80 (68.43-117.84) 95.37 (93.97-96.77) 93.49 (90.82-96.17) 0.46 (0.18, 1.17) 0.1024
 ≥50 73 1 59.44 (8.37-422.00) 97.50 (92.66-100.00) Non-estimable 0.30 (0.03, 2.55) 0.2680
Age at first delivery 0.404
 20-29 849 32 91.83 (64.94-129.85) 94.95 (92.95-96.95) 89.85 (84.92-94.78) ref
 30-39 2021 107 119.37 (98.76-144.27) 93.36 (91.99-94.73) 90.41 (88.25-92.56) 1.31 (0.88, 1.94) 0.1850
 40-49 101 6 101.27 (45.50-225.42) 96.80 (93.24-100.00) 88.75 (79.04-98.47) 1.13 (0.47, 2.69) 0.7909
Age at last delivery 0.7965
 20-29 439 19 94.77 (60.45-148.57) 95.23 (92.96-97.49) 92.30 (87.67-96.94) ref
 30-39 2396 117 113.63 (94.80-136.20) 93.66 (92.39-94.93) 90.07 (87.83-92.30) 1.16 (0.72, 1.89) 0.5389
 40-49 136 9 121.73 (63.34-233.95) 94.82 (90.75-98.90) 87.61 (78.47-96.75) 1.25 (0.57, 2.77) 0.5768
Number of delivery 0.5631
 1 1681 93 114.98 (93.83-140.89) 93.65 (92.22-95.07) 89.90 (87.54-92.27) ref
 2 1194 47 102.35 (76.90-136.22) 94.42 (92.64-96.20) 91.01 (87.09-94.94) 0.84 (0.59, 1.19) 0.3220
 >=3 96 5 138.77 (57.76-333.40) 94.05 (88.09-100.00) 86.82 (72.13-100.00) 1.13 (0.46, 2.78) 0.7894
Time-since-first-delivery <.0001
 < 5yr 477 67 152.74 (120.21-194.06) 89.73 (87.00-92.45) 85.59 (82.37-88.80) ref
 5yr-10yr 1229 57 89.78 (69.25-116.39) 95.26 (93.99-96.53) Non-estimable 0.44 (0.30, 0.64) <.0001
 >=10yr 1265 21 91.09 (59.39-139.70) Non-estimable Non-estimable 0.42 (0.24, 0.71) 0.0013
Time-since-last delivery <.0001
 < 5yr 759 87 143.17 (116.04-176.65) 91.10 (89.06-93.13) 87.16 (84.53-89.79) ref
 5yr-10yr 1508 46 79.86 (59.82-106.62) 96.01 (94.80-97.23) Non-estimable 0.44 (0.30, 0.64) <.0001
 >=10yr 704 12 99.62 (56.58-175.42) Non-estimable Non-estimable 0.53 (0.28, 1.01) 0.0546
Preeclampsia 0.5516
 No 2920 141 110.44 (93.64-130.26) 94.02 (92.93-95.11) 90.33 (88.31-92.36) ref
 Yes 51 4 145.99 (54.79-388.97) 91.55 (82.11-100.00) 85.01 (69.87-100.00) 1.35 (0.50, 3.65) 0.5516
Gestational DM 0.5560
 No 2467 119 108.53 (90.68-129.89) 94.10 (92.91-95.28) 90.10 (87.87-92.33) ref
 Yes 504 26 125.20 (85.25-183.89) 93.28 (90.55-96.02) 91.48 (88.13-94.84) 1.14 (0.74, 1.74) 0.5562

*P-value by log rank test.

**P-value by Cox PH regression.