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. 2022 Jul 1;10:918659. doi: 10.3389/fbioe.2022.918659

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Copyright © 2022 Ganesh and Maerkl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Editing mechanism for aminoacylation process. Pre-transfer editing occurs before amino acid gets charged onto tRNA. Post-transfer editing occurs after amino acid is charged onto tRNA. Trans editing factors are independent editing proteins involved in hydrolysis of mischarged tRNA.