Figure 3.

Estimation of cell–cell communication within PDAC using CellChat

(A) Heatmap showing the summary of the signaling pathways that contribute to outgoing or incoming communication. The color bar represents the relative signaling strength of a signaling pathway across cell types. The bars indicate the sum of the signaling strength of each cell type or pathway.

(B) Circle plots displaying putative ligand–receptor interactions, with the width of edges representing the strength of the communication.

(C) Chord diagram showing each ligand–receptor pattern and their weights in the interaction between CAFs and malignant cells.