TABLE 8.
Patents filed on shikonin and its derivatives.
| Sr.No. | Patent name | Scientist name | Patent number and year |
|---|---|---|---|
| 1. | Medicine containing shikonin compound as an active component (Feixin 2008) | Wang Feixin | CN100370976C, 2008 |
| 2. | Pharmaceutical composition comprising shikonin derivatives from Lithospermum erythrorhizon for treating or preventing diabetes mellitus (Hwang et al., 2010) | Ji Ho Park, Sun Yeou Kim, Tong Ho Kang Eun Ju Hwang, and Chul Hoon Kang | US20100093852A1, 2010 |
| 3. | Use of alkannin in preparing medicine for treating tumor disease (Xun and Jianping 2006) | Hu xun, and Fangjianping | CN1579378A, 2006 |
| 4. | Lithospermum and application of its active ingredient in preparing medicament for treating tumors stem cell (Xùn 2012) | Hu xun | CN101194920B, 2012 |
| 5. | Method for producing complex of shikonin compound and β-1,3–1,6-glucan (Nagasaki et al., 2018) | Ken Nagasaki, Taizo Taniguchi, Mariko Takenokuchi, Suzuki Toshio, Masanori Yanagida | JP6322784B2, 2018 |
| 6. | Application of 5,8-dyhydroxyl-2-(1-acetyl-4-methyl-3-pentenyl)-1,4-naphthoquinone diketone to preparation of medicines for resisting diabetes (Liu Chaochun 2012) | Liu Chaochun, and Zhu Banghao | CN102526016A, 2012 |
| 7. | High-optical-purity alkannin and akannin naphthazarin nuclear parent hydroxyl methylation carbonyl oxime derivative and preparation method (Li Shaoshun 2013) | Li Shaoshun, Wang Rubing and Zhang Xu | CN103130680A, 2013 |
| 8. | Preparation method of high optical purity shikonin and alkannin, and derivatives (Shaoshun and Rubing 2012) | Lishao shun and Wang rubing | CN102399139A, 2012 |
| 9. | Application of shikonin in medicine for treating acute leukemia (Zhang et al., 2014) | Zhang Bo, Chen Na, Zheng Qiusheng, Chen Hongmei and Wang Xiaoqin | CN103720679A, 2014 |
| 10. | Method for extracting shikonin from lithospermum (Liuhua 2011) | Su liu Hua | CN101973864A, 2011 |
| 11. | Application of shikonin in preparing medicine for inducing apoptosis (Weidong 2007) | Hu Xun and Han Weidong | CN1931152A, 2007 |
| 12. | Coloring method of the shikonin to wool fabric (Ming et al., 2017) | Lu ming, Lilanqian liu, Xin liu, Ping liuyiping, Fan tao and Zhaozhenyun Zhou jing | CN106758344A, 2017 |