TABLE 9.

Clinical trials registered on clinicaltrials.gov related to shikonin and shikonin producing species (source- https://clinicaltrials.gov/and Sun et al., 2022).

Sr.No.	Study title	Drug name	Conditions	Locations	Identifier
1.	Academia sinica investigator award 2010	Shikonin	Breast cancer	Taipei Medical University — WanFang hospital Taipei, Taiwan	NCT01287468
2.	The role of pyruvate kinase M2 in growth, invasion and drug resistance in human urothelial carcinoma	Shikonin	Bladder urothelial carcinoma	Department of urology, National Taiwan University hospital Taipei, Taiwan	NCT01968928
3.	A Series of N-of-1 trials of traditional chinese medicine based on bayesian method	Radix lithospermi	Bronchiectasis	Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine Shanghai, China	NCT04601792
4.	Evaluating the effects of traditional chinese medicine by N-of-1 trials	Radix lithospermi	Bronchiectasis	Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine Shanghai, Shanghai, China	NCT03147443
5.	Effectiveness of Qufeng Shengshi Fang on treatment of allergic rhinitis.	Radix lithospermi	Rhinitis, allergic, perennial	Peking Union Medical College Hospital, Traditional Chinese Medicine Department Beijing, Beijing, China	NCT02653339
6.	Study of tumor-shrinking decoction (TSD) to treat symptomatic uterine fibroids	Lithospermum erythrorhizon	Leiomyoma	School of Chinese Medicine, University of Hong Kong Hong Kong, China	NCT02189083