TABLE 3.
Genes associated with neurodegeneration in AD.
| Gene name | Transcript ID | Fold change | Regulation | Description |
| Autophagic-lysosomal | ||||
| LAMP1 | NM_005561 | 1.37 | UP | Lysosomal-associated membrane protein 1 |
| LAMP2 | NM_013995 | 1.49 | UP | Lysosomal-associated membrane protein 2 |
| CATSH | NM_004390 | 2.19 | UP | Cathepsin H |
| ULK1 | NM_003565 | −1.60 | DOWN | Unc-51-like kinase 1 |
| MAP1LC3A | NM_032514 | −1.43 | DOWN | Microtubule-associated protein 1 light chain 3α |
| Proteasome | ||||
| PSMB9 | NM_002800 | 1.49 | UP | Proteasome subunit, β type, 9 |
| MAP kinases | ||||
| MAPK8 | NM_002754 | −1.37 | DOWN | Mitogen-activated protein kinase 8 |
| MAPK10 | NM_002750 | −1.71 | DOWN | Mitogen-activated protein kinase 10 |
| MAPK13 | NM_138982 | −2.11 | DOWN | Mitogen-activated protein kinase 13 |
| Phosphorylation of tau protein | ||||
| GSK3B | NM_002093 | −1.41 | DOWN | Glycogen synthase kinase 3β |