FIGURE 7.

Accumulation in the skin of phenolic acids after 24-penetration; different letters indicate significant differences between the HEas, α = 0.05 (A). The microscopic photos of vertical slicing of porcine pig skin sections 24 h after applying the HEas. The polyphenols are visible in the upper layer of the skin, along the SC. Visible are the polyphenols blue under a fluorescence effect (blue color) (B). HEa-EtOH—hydrogel containing dry ethanolic extract of E. angustifolium; HEa-iPrOH—hydrogel containing dry isopropanol extract of E. angustifolium, HEa-WA-hydrogel containing dry water extract of E. angustifolium.