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. 2022 Jun 27;28:1610373. doi: 10.3389/pore.2022.1610373

TABLE 9.

Assessment of DCIS prognosis: University of Southern California/Van Nuys Prognostic Index (43).

Scoring 1 2 3
Tumour size (mm) ≤15 16–40 ≥41
Surgical margin (mm) ≥10 1–9 <1
Histological classification (grade) Non-HG without necrosis Non-HG with necrosis HG
Age >60 40–60 <40

With breast preservation, prognosis is good (low probability of recurrence) if the sum of scores is 4–6, moderate if it is 7–9, and poor if it is 10–12. HG: high grade (poorly differentiated). The significance of USC/VNPI, is that of an auxiliary tool for the selection of another treatment strategy after conservative surgery: cases with a high score (1012) are candidates for mastectomy, whereas cases with a score of 7–9 for radiotherapy.