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. 2022 Jun 17;13:884155. doi: 10.3389/fphar.2022.884155

FIGURE 5.

FIGURE 5

Main adverse events identified in clinical trials exploring new antidepressant agents. AE, adverse events; dBP, diastolic blood pressure; SAE, severe adverse events. Based on data from Preskorn et al. (2008); Ibrahim et al. (2012); Ghaemi et al. (2021); Fava et al. (2022); Sanacora et al. (2017); O’Donnell et al. (2021); NLM, NCT02974010; Park et al. (2020); NLM, NCT02192099; Lapidus et al. (2014); Leal et al. (2021); Huang et al. (2013); Heresco-Levy et al. (2013); Majeed et al. (2021); Nagele et al. (2015); Zarate et al. (2004); NLM, NCT00305578; Umbricht et al. (2020); Quiroz et al. (2016); NLM, NCT01145755; Axsome Therapeuticals (2019); Axsome Therapeuticals (2020); Kelly and Lieberman (2014); Fava et al. (2016); NLM, NCT03188185; Davidson et al. (2021); Drevets and Furey (2010); NLM, NCT03386448; Arnold et al. (2015); Timmers et al. (2018); Brin et al. (2020); Binneman et al. (2008).