Table 1.
Associations of childhood and adulthood circumstances with two aging measures.
| Model 1a |
Model 2b |
|||
|---|---|---|---|---|
| Coef. (95% CI) | p value | Coef. (95% CI) | p value | |
| PD (by one-SD) | ||||
| Subpopulations for childhood and adulthood circumstances | ||||
| Subpopulation 1 (less childhood trauma and adulthood adversity) | ref | — | ref | — |
| Subpopulation 2 (less born in the war era and more education) | -0·01 (-0·07, 0·07) | 0·89 | 0·01 (-0·06, 0·08) | 0·76 |
| Subpopulation 3 (good childhood relationship and more education) | 0·08 (0·02, 0·14) | 0·01 | 0·07 (0·02, 0·13) | 0·01 |
| Subpopulation 4 (more adulthood adversity and less education) | 0·12 (0·06, 0·18) | <0·0001 | 0·10 (0·05, 0·16) | <0·0001 |
| Subpopulation 5 (more born in the war era and less education) | 0·16 (0·10, 0·22) | <0·0001 | 0·11 (0·05, 0·17) | <0·0001 |
| Subpopulation 6 (more childhood trauma and adulthood adversity) | 0·17 (0·09, 0·24) | <0·0001 | 0·14 (0·06, 0·21) | <0·0001 |
| Proportion of obesity | 0·07 (0·01, 0·13) | 0·02 | ||
| Smoking | ||||
| Non-smoker | ref | |||
| Ever smoker | 0·04 (-0·02, 0·11) | 0·22 | ||
| Current smoker | -0·02 (-0·08, 0·04) | 0·55 | ||
| Drinking | ||||
| Non-drinker | ref | |||
| Drinker | -0·01 (-0·05, 0·04) | 0·80 | ||
| FI (by one-point) | ||||
| Subpopulations for childhood and adulthood circumstances | ||||
| Subpopulation 1 (less childhood trauma and adulthood adversity) | ref | — | ref | — |
| Subpopulation 2 (less born in the war era and more education) | 0·01 (-0·00, 0·02) | 0·16 | 0·02 (0·01, 0·03) | <0·0001 |
| Subpopulation 3 (good childhood relationship and more education) | 0·007 (-0·002, 0·016) | 0·14 | 0·01 (-0·00, 0·02) | 0·14 |
| Subpopulation 4 (more adulthood adversity and less education) | 0·08 (0·07, 0·09) | <0·0001 | 0·074 (0·066, 0·083) | <0·0001 |
| Subpopulation 5 (more born in the war era and less education) | 0·06 (0·05, 0·07) | <0·0001 | 0·04 (0·03, 0·05) | <0·0001 |
| Subpopulation 6 (more childhood trauma and adulthood adversity) | 0·10 (0·09, 0·12) | <0·0001 | 0·10 (0·09, 0·11) | <0·0001 |
| Proportion of obesity | 0·05 (0·04, 0·06) | <0·0001 | ||
| Smoking | ||||
| Non-smoker | ref | — | ||
| Ever smoker | 0·03 (0·02, 0·04) | <0·0001 | ||
| Current smoker | 0·008 (-0·001, 0·018) | 0·08 | ||
| Drinking | ||||
| Non-drinker | ref | — | ||
| Drinker | 0·004 (-0·003, 0·010) | 0·29 | ||
CI = confidence interval. PD = physiological dysregulation. SD=standard deviation. FI=frailty index.
a
Model 1 was unadjusted.
b
Model 2 was adjusted for chronological age, gender, proportion of obesity, smoking status, and drinking status.