Table 2.
Clinical course after ascites as index decompensation event in the study cohort (n = 622).
| Value | |
|---|---|
| Patients, n (%) | 622 (100%) |
| Time of follow-up (months), median (IQR) | 71.5 (62.0–80.5) |
| Any further decompensation, n (%) | 350 (56%) |
| First further decompensation event, n (%) | |
| Refractory ascites | 130 (21%) |
| SBP | 32 (5%) |
| HRS-AKI | 29 (5%) |
| Variceal bleeding | 27 (4%) |
| Hepatic encephalopathy | 112 (18%) |
| More than one decompensation event | 20 (3%) |
| All further decompensation events, n (%) | |
| Refractory ascites | 204 (33%) |
| SBP | 105 (17%) |
| HRS-AKI | 81 (13%) |
| Variceal bleeding | 54 (9%) |
| Hepatic encephalopathy | 183 (29%) |
| Hyponatraemia∗, n (%) | 176 (28%) |
| ACLF, n (%) | 146 (23%) |
| PVT, n (%) | 62 (10%) |
| HCC, n (%) | 79 (13%) |
| TIPS, n (%) | 81 (13%) |
| LT, n (%) | 105 (17%) |
| Death, n (%) | 262 (42%) |
| Liver-related | 224 (85%) |
| Non-liver-related | 36 (14%) |
| Unknown | 2 (1%) |
ACLF, acute-on-chronic liver failure; HCC, hepatocellular carcinoma; HRS-AKI, hepatorenal syndrome–acute kidney injury; LT, liver transplantation; PVT, portal vein thrombosis; SBP, spontaneous bacterial peritonitis; TIPS transjugular intrahepatic portosystemic shunt.
∗
Defined as serum sodium <130 mmol/L.