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. 2022 Jun 3;4(8):100513. doi: 10.1016/j.jhepr.2022.100513

Table 3.

Risk factors for mortality in patients with ascites as the index decompensation event.

Patient characteristics Univariable
Overall cohort
Model 1
Subgroup ascites grade 2
Model 2
Subgroup ascites grade 3
Model 3
SHR (95% CI) p value aSHR (95% CI) p value aSHR (95% CI) p value aSHR (95% CI) p value
Age (year) 1.03 (1.01–1.05) <0.001 1.04 (1.02–1.06) 0.002 1.04 (1.01–1.07) 0.009 1.04 (1.02–1.06) 0.002
Inclusion time
 2000–2013 1
 2014–2021 1.17 (0.96–1.38) 0.140
MELD (point) 1.04 (0.99–1.09) 0.180 1.04 (0.97–1.11) 0.320 1.04 (1.02–1.06) 0.002 1.03 (0.93–1.13) 0.550
Albumin (g/L) 0.96 (0.94–0.98) <0.001 0.98 (0.97–0.99) <0.001 0.96 (0.94–0.98) <0.001 0.99 (0.95–1.03) 0.600
Platelets (g/L) 1.00 (1.00–1.00) 0.830
Haemoglobin (g/L) 0.93 (0.79–1.07) 0.320

Univariable and multivariable competing risk regression analysis for mortality, including age, aetiological cure of liver disease, inclusion time, MELD, and albumin in the study cohort (model 1), grade 2 ascites (model 2), and grade 3 ascites (model 3). Values in bold denote statistical significance.

aSHR, adjusted subdistribution hazard ratio; MELD, model for end-stage liver disease; SHR, subdistribution hazard ratio.