Figure 3.

Comparison of the progression of logMAR visual acuity among patients with autosomal recessive retinitis pigmentosa carrying eyes shut homolog (EYS) gene variants at different locations. (A, B) Visual acuity of the right (A) and left eyes (B) at the first visit, presented as a function of age. Every point represents an individual patient in our cohort. The blue and red lines are the linear regression lines for groups B and C, respectively. (A) The coefficients for age in groups B and C are 0.0031 and 0.048, respectively. (B) The coefficients for age in groups B and group C are –0.001 and 0.041, respectively. The group C patients, who have variants near the C-terminus, had a more severe disease progression than the group B patients, who have one variant near the N-terminal domain and the other in the C-terminal laminin G containing domain (c.5647-c.9495). OD, right eye; OS, left eye.