Table 1.

NOS scores

Study	Selection	Comparability	Outcome	NOS score	Definition of sepsis used
Pittet34 1993	★★	★★	★★	6	Septicemia was defined as a clinical condition associated with one or more positive blood cultures for a commonly accepted pathogen or two or more positive blood cultures for less usual pathogens (coagulase negative staphylococci and candida spp) and either signs of severe infection or evidence of systemic response to severe infection
Salive35 1993	★★	★★	★★★	7	Septicemia was defined as a clinical condition associated with one or more positive blood cultures for a commonly accepted pathogen or two or more positive blood cultures for less usual pathogens (coagulase negative staphylococci and candida spp) and either signs of severe infection or evidence of systemic response to severe infection
Alroumi25 2018	★★★	★★	★	6	The sepsis-2 consensus definitions were utilized
Kempker26 2018	★★	★★	★★	6	Sepsis is defined as a dysregulated immune response to infection that results in acute organ dysfunction
Pehlivanlar27 2021	★★★	★★	★★	7	Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection