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. Author manuscript; available in PMC: 2022 Jul 15.
Published in final edited form as: Nature. 2002 Feb 28;415(6875):1030–1034. doi: 10.1038/4151030a

Table 1.

Number and phenotype of GFP+ cells

Property of cells Control 48 h
(n = 5)
Running 48 h
(n = 5)
Control 4 weeks
(n = 5)
Running 4 weeks
(n = 8)
GFP+ cells 265 (66) 260 (45) 87 (22) 130 (38)
Spread (mm) 1.54 (0.16) 1.58 (0.16) 1.82 (0.28) 1.47 (0.21)
NeuN (%) 0 0 2.2 (1.3) 27.4 (9.3)**
Calbindin (%) 0 0 2.0 (1.2) 22.5 (9.3)**
Tuj1-β (%) 9.2 (1.1) 28.4 (8.3)* 15.6 (6.9) 31.7 (3.6)*
NG2 (%) 26.0 (12.2) 35.0 (2.3)* 7.7 (5.0) 13.7 (3.8)
GFAP (%) 4.1 (1.9) 4.6 (3.6) 10.3 (4.2) 8.6 (1.5)

The total number of GFP+ cells from the dentate gyrus is shown at indicated time points after viral injection. At 48 h, runners had a greater percentage of GFP+ cells labelled for Tuj1-β (P < 0.04) and NG2 (P < 0.05) than controls. At 4 weeks, the percentage of GFP+ cells co-labelling with neuronal markers was significantly higher in runners than in controls (NeuN, P < 0.01; calbindin, P < 0.01; Tuj1-β, P < 0.04). All data are presented as means, with s.e.m. in parentheses. Asterisk, P < 0.05; double asterisk, P < 0.01.