Detection of rhamnosylation in EF-P. (A)
Schematic representation
of the rhamnosylation and subsequent LysC digestion of EF-P. (B) Event
characteristics after the addition of a mixture of synthetic peptides
([1], [2], [3], and [4]). (C) Event characteristics after addition of Lys-C digested
unmodified EF-P. (C) Event characteristics after addition of Lys-C
digested rhamnosylated EF-P. The location of the event clusters [f], [1], [2], [3],
and [3m] are indicated in the Iex% histogram, and the event clusters belonging
to peptide [3] and [3m] are highlighted in yellow and red, respectively. Measurements
in 3 M LiCl, buffered to pH 3.8, at −50 mV applied voltage.
Data were recorded with a 50 kHz sampling frequency and a 10 kHz Bessel
filter.