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. 2022 Jul 15;13:295. doi: 10.1186/s13287-022-02975-0

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6. — Micro-CT imaging analysis of the different groups at 2, 4, and 8 weeks postoperatively. The cross-sectional micro-CT images of the bone tunnel at the femoral side (A) and tibial side (B). Relative tunnel area at the femoral (C) and tibial (D) sides and the bone volume/total volume ratio (BV/TV) at the femoral (E) and tibial (F) sides for ACLR at 2, 4, and 8 weeks postoperatively among the control group, the BMSC-Exos group and the BMSC-Exos mimic group. Data are presented as mean ± SD. Statistical analysis was performed with one-way ANOVA followed by Tukey’s multiple comparisons test. n = 6. *P < 0.05, **P < 0.01.