Table 2.
US cost per hospitalization day for Grade 3/4 adverse events, symptomatic skeletal events, and end-of-life care
| Event | US cost per hospitalization day |
|---|---|
| Diarrhea | $4134 (€3514)a |
| Infection | $2422 (€2059)a |
| Renal disorder | $2928 (€2489)a |
| Cardiac disorder | $3282 (€2790)a |
| Febrile neutropenia | $4685 (€3982)a |
| Anemia | $6111 (€5194)b |
| Thrombocytopenia | $5099 (€4334)b |
| Hyponatremia | $5232 (€4447)b |
| Pathological fracture | $6277 (€5335)a |
| Spinal cord compression | $9276 (€7885)a |
| End of life | $5939 (€5048)c |
Abbreviations: ICU intensive care unit, US United States
ICU costs were assumed to be part of the hospitalization costs
aTo obtain the respective cost, hospitalization costs per event were divided by the length of stay or expected days of hospitalization (based on clinician input) (Supplementary Appendix 5)
bAdapted from Bilir et al. (2016) [28]
cAdapted from Wilson et al. (2014) [27]