Table 4:

Results from multivariable regression models to investigate independent associations of HIV and extent of pain with each self-reported sleep parameter and abnormal ODI: Model 1 – main effects only; Model 2 – including additional adjustment for age, gender, ethnicity, HIV exposure group and educational attainment; Model 3 – including additional adjustment for substance use, pain relief and sleep medication.

Sleep parameter		Model 1		Model 2		Model 3
	Parameter	Estimate (SE)	p-value	Estimate (SE)	p-value	Estimate (SD)	p-value
ISI (continuous)	HIV	2.29 (0.66)	0.0006	2.42 (0.74)	0.001	2.12 (0.73)	0.004
	Non-widespread pain	2.45 (0.64)	0.0001	2.44 (0.64)	0.0002	2.29 (0.64)	0.0004
	Widespread pain	5.29 (0.84)	0.0001	5.35 (0.87)	0.0001	4.37 (0.90)	0.0001
PROMIS-SD T-score	HIV	2.76 (0.96)	0.004	3.75 (1.06)	0.0005	3.47 (1.07)	0.001
	Non-widespread pain	3.14 (0.92)	0.0007	3.08 (0.92)	0.0009	2.85 (0.92)	0.002
	Widespread pain	5.87 (1.21)	0.0001	5.53 (1.25)	0.0001	4.55 (1.30)	0.0005
PROMIS-SRI T-score	HIV	4.66 (0.96)	0.0001	4.58 (1.07)	0.0001	4.31 (1.09)	0.0001
	Non-widespread pain	3.94 (0.92)	0.0001	3.96 (0.93)	0.0001	3.83 (0.94)	0.0001
	Widespread pain	8.68 (1.21)	0.0001	8.84 (1.25)	0.0001	8.10 (1.32)	0.0001
		OR (95% CI)	p-value	OR (95% CI)	p-value	OR (95% CI)	p-value
RLS	HIV	1.01 (0.53, 1.94)	0.98	1.26 (0.61, 2.61)	0.54	1.29 (0.62, 2.71)	0.50
	Non-widespread pain	1.94 (0.99, 3.80)	0.05	1.84 (0.93, 3.64)	0.08	1.81 (0.91, 3.61)	0.09
	Widespread pain	2.70 (1.23, 5.94)	0.01	2.34 (1.03, 5.30)	0.04	2.28 (0.96, 5.40)	0.06
Insomnia	HIV	3.58 (1.57, 8.17)	0.002	3.50 (1.43, 8.55)	0.006	3.25 (1.31, 8.06)	0.01
	Non-widespread pain	2.17 (1.11, 4.23)	0.02	2.16 (1.10, 4.25)	0.03	2.04 (1.03, 4.05)	0.04
	Widespread pain	4.60 (2.18, 9.68)	0.0001	5.03 (2.31, 10.97)	0.0001	3.68 (1.62, 8.36)	0.002