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. 2022 Jul 12;2022(7):CD010834. doi: 10.1002/14651858.CD010834.pub4

Comparison 4. Reslizumab (SC) versus placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
4.1 Rate of exacerbations requiring systemic corticosteroids 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.1.1 Eosinophilic 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.2 Rate of exacerbations requiring emergency department treatment or admission 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.2.1 Eosinophilic 1   Rate Ratio (IV, Fixed, 95% CI) Totals not selected
4.3 Health‐related quality of life (AQLQ mean difference) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.3.1 Eosinophilic 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.4 Health‐related quality of life (ACQ mean difference) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.4.1 Eosinophilic 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.5 Health‐related quality of life (SGRQ mean difference) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.5.1 Eosinophilic 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.6 Pre‐bronchodilator FEV 1 (litres) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.6.1 Eosinophilic 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.7 Serious adverse events 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.7.1 Eosinophilic 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.8 Adverse events leading to discontinuation 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.8.1 Eosinophilic 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected
4.9 Blood eosinophil level (cells × 10⁹/litre) 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected
4.9.1 Eosinophilic 1   Mean Difference (IV, Fixed, 95% CI) Totals not selected