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MiR‐148a was functionally transferred into chondrocytes and epithelial cells by milk‐derived EVs. Chondrocytes and A549 cells were transfected with a miR‐148a luciferase‐based reporter construct and stimulated with CMEVs for up to 72 h. Fluorescence was measured in chondrocytes (A) and A549 epithelial cells (B) exposed to different concentrations of CMEVs. C) Additionally, DNMT‐1 expression was measured 24 h after stimulation. Error bars represent mean ±SD, **p>0.005, ***p>0.0005.
