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Schematic overview of glucocorticoid receptor (GR) signaling pathway. Glucocorticoids can bind to the GR and exert their effects by genomic (main pathway) and non‐genomic mechanisms. When inside the nucleus, the GR can cause either transactivation or transrepression of target genes. CBG, corticosteroid‐binding globulin; GRE, glucocorticoid response elements; hsp, heat shock protein; nGRE, negative glucocorticoid response elements; TF, transcription factors
