TABLE 5.
Pooled regression coefficients
| k cohorts | n participants | Analysis method | Pooled beta | 95% CI | Between‐study heterogeneity | ||
|---|---|---|---|---|---|---|---|
| Q w | P‐value | ||||||
| HairF independent—BMI dependent | 8 | 1,984 | CLIA | 0.02 | 0.016; 0.03 | 0.26 | >0.05 |
| 26 | 11,635 | LC–MS | 0.05 | 0.045; 0.054 | 0.50 | >0.05 | |
| HairF independent—BMI SDS dependent | ‐ | ‐ | CLIA | ‐ | ‐ | ||
| 6 | 998 | LC–MS | 0.20 | 0.14; 0.27 | 0.11 | >0.05 | |
| HairF independent—WC dependent | 4 | 1,556 | CLIA | 0.02 | 0.02; 0.03 | 0.13 | >0.05 |
| 10 | 4,259 | LC–MS | 1.26 | 1.08; 1.44 | 0.15 | >0.05 | |
| HairF independent—WHR dependent | ‐ | ‐ | CLIA | ‐ | ‐ | ||
| 5 | 1,805 | LC–MS | −0.01 | −0.01; −0.00 | 0.00 | >0.05 | |
| HairE independent—BMI dependent | CLIA | ‐ | ‐ | ||||
| 9 | 5,266 | LC–MS | 1.15 | 0.98; 1.31 | 0.08 | >0.05 | |
| HairE independent—WC dependent | CLIA | ‐ | ‐ | ||||
| 6 | 3,102 | LC–MS | 11.0 | 10.1; 11.9 | 0.05 | >0.05 | |
Note: ‐, meta‐analysis not performed due to insufficient number of cohorts. Bold text indicates statistically significant effect (P‐value < 0.05).
Abbreviations: CI, confidence interval; HairF, hair cortisol; HairE, hair cortisone; SDS, standard deviation score; WC, waist circumference; WHR, waist‐to‐hip ratio; LC–MS, liquid chromatography‐(tandem) mass spectrometry; CLIA, chemiluminescent immunoassay.