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Blocking laminin alpha-3 results in delayed blistering at 72 h. Ex vivo 3D human skin equivalents were treated with laminin alpha-3 blocking antibody (clone: P3H9-2) or vehicle control (n=3/condition). Cultures were harvested for histology at 24 and 72 h, revealing blistering at 72 h, but not 24. Scale bars =50 µm
