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. 2022 Apr 5;35(6):e15453. doi: 10.1111/dth.15453

TABLE 1.

Main dermal filler products discussed in this review, all commonly used in the UK

Brand Product Concentration of HA (mg/ml) Crosslinking technology Percent crosslinking Degree of correction and (site of application) a
Revolax Fine 24 21 Ursolic acid encapsulation 21 Unreported Fine, superficial and lip submucosa (crow's feet, neck, and wrinkles)
Deep 24 21 Ursolic acid encapsulation Unreported Fine to medium, superficial to mid dermis (forehead lines, tear troughs)
Sub‐Q 24 21 Ursolic acid encapsulation Unreported Moderate to severe, mid to deep dermis (facial contours, cheek, nose, chin)
Teoxane

Redensity II

RHA 1

RHA2

15 43

15 44

23 44

Standard

RHA 33

RHA

Unreported

1.9% 45

3.6% 45

Fine, superficial (tear trough, periorbital regions)

Dynamic perioral rhytids and barcode lines

Dynamic lip volumization

RHA3 23 44 RHA 6.02% 45 Moderate to severe, mid to deep dermis (deep wrinkles)
RHA4 23 44 RHA 6.85% 45 Moderate to severe, deep dermis to subcutaneous (cheek, chin, temples)
Ultra‐deep 25 14 Standard 10% 45 Severe, deep dermis (chin, cheekbones, jawline)
Juvéderm Vobella 15 44 Vycross 44 6.61% 45 Fine to medium, superficial to mid dermis and lip submucosa (lateral canthal lines, tear troughs, lips)
Volift 17.5 44 Vycross 7.73% 45 Medium, midface volume loss and cheek augmentation, deep dermis to subcutaneous (cheek, facial contours, lips)
Voluma 20 44 Vycross 7.36% 45 Medium, midface volume loss and cheek augmentation, deep dermis to subcutaneous (temple and lateral brow, medial brow, cheek, jawline)
Volux 25 44 Vycross 9.4% 45 Moderate to severe, deep dermis (temple and lateral brow, medial brow, cheekbones, jawline)
Restylane Fynesse 20 44 OBT 32 0.1%–5% 19 Fine to medium, superficial to mid dermis and lip submucosa (nasolabial folds, lips)
Volyme 20 44 OBT 0.1%–5% 19 Moderate to severe, deep dermis to subcutaneous (temple and lateral brow, cheek, chin)
Refyne 20 44 OBT 6% 30 Moderate to severe, mid to deep dermis (lateral canthal lines, tear trough)
Defyne 20 44 OBT 8% 30 Moderate to severe, mid to deep dermis (temple and lateral brow, cheek, medial brow, jawline)

Abbreviation: HA, hyaluronic acid.

a

Based on product information provided by manufacturers.