TABLE 2a.

Outcome measures at the different timepoints

Measures	Trial period				Follow‐up
	T0	T1	T2	T3	T4		T5 c	T6 c
	0 weeks	12 weeks	26 weeks	52 weeks	104 weeks		156 weeks	208 weeks
General characteristics	X
Primary outcome	X			X	X		X	X
Secondary outcomes
(a) Function	X		X	X	X		X a	X a
(b) Quality of life	X		X	X		X	X	X
(c) Health care usage and costs	X	X	X	X	X		X	X
(d) Perceived effect and satisfaction with treatment				X b	X b		X b	X b

^a The 6MWT will not be measured at T5 and T6.

^b In control group only if physical therapy has been used.

^c Or end of study for participants included after 12 months after start of the study.