TABLE 1.

Overview of simulation parameters

Type	Parameter	Value
Lattice	Dimension	256 x 256 pixels
	Size	70 x 70 μm2
RBCs	Radius	3.5 μm (circular RBCs) 24
	Minimum interspace	0.55 μma
	Number	Varying with hematocrit (46 RBCs for hematocrit of 36%)
	Magnetic susceptibility	−0.736*10−6 ppm cgs (assuming Y = 100%) 17
	T 1	1 sb
	T 2	Varying with field strength (200/117/50*10−3 s for B0 of 1.5/3/7 T) 14
	Proton concentration	0.7
Blood plasma	Magnetic susceptibility	−0.722*10−6 ppm cgs 17
	T 1	1 sb
	T 2	Varying with field strength (1,194/500/304*10−3 s for B0 of 1.5/3/7 T) 14
	Proton concentration	0.95
Contrast agent	r 1 (T 1 relaxivity)	0 mM−1 s‐1b
	r 2 (T 2 relaxivity)	Varying with field strength (4.6/5.2/4.8 mM−1 s−1 for B0 of 1.5/3/7 T) 25 , 26
	Diffusivity	48.5*10−11 m2 s−1 (default Dfree) 5
	Permeability	0 s‐1
	Magnetic susceptibility	4π*2.55*10−8 mM−1 2
MRI	TE	20*10−3/40*10−3 s (gradient‐echo/spin‐echo)
	TR	1 s
	Excitation time	0 s
	FA	90°/90°–180° (gradient‐echo/spin‐echo)
	Phase angle	0°
	Static magnetic field	Varying (1.5/3/7 T)
Other	Water diffusivity	760*10−12 m2 s−1 (default Dfree) 5

^a to prevent overlap of red blood cells (RBCs).

^b to minimize T1 effects to reflect complete refreshment of flowing blood.