Figure 8.
Design of an ATP DNA nanoplier aptasensor. Top: schematic showing DNA nanoplier reconfiguration driven by the capture of two ATP molecules. The inner faces of the arms contained dye‐labeled split aptamer strands (green and red), such that the binding of two ATP molecules triggered a reconfiguration from open nanoplier to a closed state. Bottom: ATP capture characterized by AFM and fluorescence microscopy, as shown in representative images here. Reproduced with permission.99 Copyright 2017, American Chemical Society.