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Each node represents a unique haplotype, the diameter of the node is proportional to the haplotype frequency and links between adjacent nodes belong to the union of all minimum spanning trees (a) Low diversity intra-host HCV HVR1 population from PK-9 (0.00512), genotype 3a; (b) average diversity population from PK-20 (0.0142), genotype 1b; (c) high diversity population from PK-23 (0.0226), genotype 3a.
