FIGURE 2.
EP1 receptor inhibition does not alter the gene expression of fibrotic markers in UUO mice. Mice were subject to 7 days of UUO and treated with SC‐19220 (25 mg/kg) via IP injection. Afterwards, gene expression of (A) fibronectin (FN), (B) alpha‐smooth muscle actin (αSMA), (C) collagen 1a1 (Col‐1a1) and (D) collagen 3a1 (Col‐3a1) was studied by qPCR. Relative expression was calculated using the reference gene 18S (n = 10). Data are presented as means ± SEM; ***P < .001