Figure 4.

Evaluation of DNGs as DDSs for cancer treatment. a) In vitro DOX release in PBS for all three core functional DNGs. b) Cytotoxicity screening of pure DNGs on two noncancerous and pancreatic cancer cell lines. Several other cell lines were also tested see ESI Figure S3 in the Supporting Information. AlamarBlue assay was used and cells were with substrate for 72 h. c) Cytotoxicity induced by free DOX and DOX‐DNGs against a panel of cancer cell lines with 72 h incubation.