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. 2021 Oct 13;17(3):e12859. doi: 10.1111/ijpo.12859

TABLE 3.

Panel of 15 plasma metabolite variables at 3 months most strongly associated with truncal: peripheral fat ratio at 2 years

All Individuals Boys Girls
Metabolite variables m/z Retention time (min) p‐value Corrected p‐value Fold change p‐value Fold change p‐value Fold change
LysoPS(22:2) 578.3481 0.49 5.99 × 10−06 a , b 2.16 × 10−05 a , b 1.48 4.95 × 10−05 1.58 0.021 1.37
Unkown 1015.6761 0.39 a , b 2.28 × 10−05 a , b 3.79 × 10−05 a , b 1.57 0.0002 1.64 0.033 1.49
Dimethylarginine 203.0533 0.33 0.0001 b 0.0002 b 1.85 0.0001 2.20 0.074 1.50
C24H30O8 447.2815 0.47 0.0002 b 0.0003 b 1.65 0.0009 1.80 0.032 1.49
C13 isotope of C30H40O8 530.3357 0.52 0.0003 b 0.0003 b 1.31 0.0069 1.26 0.016 1.36
C27H38O9 507.3104 0.50 0.0004 b 0.0007 b 1.31 0.0015 1.36 0.072 1.26
Unknown 431.2617 0.39 0.0005 b 0.0007 b 1.38 0.0003 1.50 0.104 1.26
LysoPE(20:1) 508.3468 0.66 0.0008 b 0.0005 b 1.09 0.0053 1.08 0.059 1.09
Unknown 590.3393 0.47 0.0018 0.0017 1.48 0.0063 1.49 0.052 1.47
LysoPG(16:0) 486.2760 0.54 0.0022 0.0026 1.14 0.0240 1.11 0.054 1.17
C30H40O8 529.3246 0.47 0.0034 0.0034 1.60 0.0075 1.73 0.114 1.46
LysoPA(22:1) 495.3132 0.86 0.0040 0.0051 1.41 0.0122 1.42 0.101 1.39
Unknown 200.8896 0.319 0.0043 0.0031 0.91 0.0066 0.91 0.069 0.90
Unknown 162.9649 0.367 0.0046 0.0075 2.03 0.0021 2.76 0.418 1.29
Unknown 222.8750 0.38 0.0050 0.0022 0.87 0.1124 0.95 0.006 0.79

Note: ‘p‐value’ are the unadjusted p‐values. ‘Corrected p‐values’ have been adjusted for sex, birth weight and feeding type. All p‐values were calculated using generalized linear models comparing high and low tertiles of trunk: peripheral ratio. Fold change is calculated relative to the ‘low’ group. Putative annotations: C24H30O8 – Esterone Glucoronide, C27H38O9 –Hydroxyprogesterone Glucoronide, C30H40O8 – Hydroxypentaoxolanostenoic acid.

Abbreviations: LysoPA, lysophosphosphatidic acid; LysoPE, lysophosphatidylethanolamine; LysoPG, lysophosphatidylglycerol; LysoPS, lysophosphatidylserine; m/z, mass‐to‐charge ratio.

a

Passing FDR based on Bonferoni.

b

Passing FDR based on Benjamini‐Hochberg.