Table 3.
Association between PDGF-BB levels and WMH volume in APOE4 carriers.
| Variable | Multivariable (all variables entered in the model) | ||||||
|---|---|---|---|---|---|---|---|
| Unstandardized Coefficients | Standardized Coefficients | t | Sig. | 95.0% Confidence Interval for B | |||
| B | Std. Error | β Beta | Lower Bound | Upper Bound | |||
| Age (Years) | 0.028 | 0.012 | 0.540 | 2.31 | 0.037 | 0.002 | 0.055 |
| Sex (Male) | -0.622 | 0.315 | -0.793 | -1.98 | 0.068 | -1.297 | 0.053 |
| PDGF-BB (pg/mL) | 0.421 | 0.133 | 0.585 | 3.16 | 0.007 | 0.135 | 0.707 |
| ICV (cm3) | 0.001 | 0.001 | 0.427 | 1.17 | 0.261 | -0.001 | 0.003 |
Note: APOE4 = apolipoprotein-e4 (APOE4) allele carrier; PDGF-BB = platelet-derived growth factor BB; ICV = intracranial volume. Bold values indicate significant predictors of WMH volume. B represents the unstandardized regression coefficient and β represents the standardized regression coefficient.