Fig. 1. Flowchart of data cleaning and aggregation.

Note that totals in the yellow boxes do not add up to the numbers in the gray boxes due to uncertain menopause stage (n = 1522), currently or recently lactating (n = 2498), having had a hysterectomy (n = 43), discrepant responses (e.g., self-reported period details did not align with self-reported menstrual group), and the divisions made to the samples. Further details can be found in the Supplementary Materials. dx, diagnosis.